Research

  • Research
  • 2022 Publication

1-  Title  High Grade Epithelial Ovarian Cancer: Overcoming Chemotherapy Resistance with Omani Marine Compounds
    Principal Investigator  Dr. Ikram Burney    
    Co-Investigator  Dr. Shadia Al-Bahlani
    Code    HM/MED/17/01  
    Date    2017-2019
    Value & Project Funder    OMR 75,000 by HM fund


2-   Title  Enhancing Prostate Cancer Sensitivity to TRAIL anti-tumor Effects by Targeting CXCR4
    Principal Investigator Dr. Ibrahim Younos  
    Co-Investigator    Dr. Shadia Al-Bahlani
    Code G/MED/PHAR/16/01 D
    Date    2016-2017
    Value & Project Funder     OMR 15,000 by SQU fund


3-  Title  Anticancer effect of Boswellia Sacra (Frankincense) on Ovarian Cancer Cell resistance to Cisplatin-induced apoptosis
    Principal Investigator  Dr. Shadia Al-Bahlani
    Code  IG/MED/ALIE/16/01 
    Date    2016-2017
    Value & Project Funder    OMR 8,000  by SQU fund


4-  Title  The role of E2F Transcription Factor 1 (E2F1) activation and its modulation by Protein Kinase B (Akt/PKB) pathway in Breast Cancer
    Principal Investigator  Dr. Shadia Al-Bahlani
    Code    IG/MED/PATH/14/01 
    Date    2014-2015
    Value & Project Funder    OMR 15,500 by SQU fund


5-   Title    Inhibition of receptor tyrosine kinase via Pgrmc1 a potential therapeutic target in gastric cancer and received initial acceptance
    Principal Investigator  Dr. Ikhlas Ahmed    
    Co-Principal Investigator    Dr. Shadia Al-Bahlani
    Code    IG/MED/PHAR/14/01             
    Date    2014-2015     
    Value & Project Funder    OMR 12,500  by SQU fund


6-  Title    The role of E2F Transcription Factor 1 (E2F1) activation and its modulation by Protein Kinase B (Akt/PKB) pathway in Breast Cancer
    Principal Investigator    Dr. Shadia Al-Bahlani
    Code  DVC-PSR/DR/2013/117
    Date    2014-2015
    Value & Project Funder    OMR 2400 by FURAP/TRC


7-  Title  Inhibition of receptor tyrosine kinase via Pgrmc1 a potential therapeutic target in gastric cancer and received initial acceptance
    Principal Investigator  Dr. Shadia Al Bahlani
    Code  IG/MED/PHAR/14/01
    Date    2014-2015
    Value & Project Funder    OMR 12,500 by SQU


8-   Title  Renal oxidative DNA damage and renal, plasma and urinary biomarkers in rats with potassium bromate nephrotoxicity: Influence of gum acacia treatment
    Principal Investigator  Prof. BaderAdin Ali
    Co-Principal Investigator   Dr. Shadia Al Bahlani
    Date  2014- 2016
    Value & Project Funder    OMR 11,250 by SQU


9-   Title Testing the Bregs cell hypothesis in sickle cell disease: Implications for pathogenesis
    Principal Investigator    Prof. Mohamed-Rachid Boulassel
    Date   2014-2016
    Value & Project Funder  OMR 83520


10-   Title Understanding the cross-talk among regulatory immune cells in lymphomas: A link to improve the efficacy of immunotherapeutic strategies
    Principal Investigator  Prof. Mohamed-Rachid Boulassel
    Date    2014-2016
    Value & Project Funder  OMR 21000


11-    Title The role of Phospholipase A2 receptor in the diagnosis of membranous glomerulopathy
    Principal Investigator    Dr. Nasar Al-Wahaibi
    Date     2014-2015
    Value & Project Funder    OMR 2400

Research Publications & Books

Journal Publications

  1. Shika Hanif Malgundkar, Nada Abdullah Hassan, Hala Al Badi, Ishita Gupta, Ikram A Burney, Zainab Al Hashami, Hamida Al Barwani, Hamad Al Riyami, Moza Al Kalbani,Ritu Lakhtakia, Aikou Okamoto, Yahya Tamimi. Identification and validation of a novel long non-coding RNA (LINC01465) in ovarian cancer. Human Cell, 2022, 1-13.doi:10.1007/s13577-022-00842-x.

 

  1. Najwa Al Balushi, Syed Imran Hassan, Nada Abdullah, Buthaina Al Dhahli, Shadia Al Bahlani, Ikhlas Ahmed, Benjamin K Tsang, Sergey Dobretsov, Yahya Tamimi, Ikram A Burney. Addition of Gallic Acid Overcomes Resistance to Cisplatin in Ovarian Cancer Cell Lines. Asian Pacific Journal of Cancer Prevention, 2022, 23 (8), 2661-2669

 

 

  1. A Al Saqri, SH Malgundkar, F Al Kindi, I Gupta, M Al Moundhri, Y Tamimi.

SOCS3 gene silencing does not occur through methylation and mutations in gastric cancer. Human Cell. 2022; 35 (4), 1114-1125

 

  1. M Al-Khaduri, A Ahmed, F Zadjali, Y Al Farsi, Y Tamimi. Association of THADA Gene Variants With Polycystic Ovarian Syndrome Clinical Manifestations in Women of Arab Ethnicity. Endocrine Practice. 2022; 28 (12), S55-S56. Abstract# 1318348.

 

  1. l Mahrouqi S, Gadalla A, Al Azri S, Al-Hamidhi S, Al-Jardani A, Balkhair A, Al-fahdi A, Al Balushi L, Al Zadjali S, Al Marhoubi AMN, Babiker HA.(2022) Drug resistant Mycobacterium tuberculosis in Oman: resistance-conferring mutations and lineage diversity. PeerJ 10:e13645 https://doi.org/10.7717/peerj.13645

 

  1. Al-Mahrouqi S, Ahmed R, Al-Azri S, Al-Hamidhi S, Balkhair AA, Al-Jardani A, Al-Fahdi A, Al-Balushi L, Al-Zadjali S, Adikaram C, Al-Marhoubi A, Gadalla A, Babiker HA. (2022) Dynamics of Mycobacterium tuberculosis Lineages in Oman, 2009 to 2018. Pathogens, 11(5):541. doi: 10.3390/pathogens11050541. PMID: 35631062; PMCID: PMC9148118.

 

  1. Said, E. A., Al-Dughaishi, S., Al-Hatmi, W., Al-Reesi, I., Al-Riyami, M., Al-Balushi, M. S., Al-Bimani, A., Al-Busaidi, J. Z., Al-Khabori, M., Al-Kindi, S., Procopio, F. A., Al-Rashdi, A., Al-Ansari, A., Babiker, H., Koh, C. Y., Al-Naamani, K., Pantaleo, G., & Al-Jabri, A. A. (2022). Human macrophages and monocyte-derived dendritic cells stimulate the proliferation of endothelial cells through midkine production. PLoS One, 17(4), e0267662. https://doi.org/10.1371/journal.pone.0267662

 

  1. Al-Hamidhi S, Parveen A, Iqbal F, Asif M, Akhtar N, Elshafie EI, Beja-Pereira A, Babiker HA. (2022) Diversity and Genetic Structure of Theileria annulata in Pakistan and Other Endemic Sites. Pathogens,11(3):334. doi:10.3390/pathogens11030334. PMID: 35335658; PMCID: PMC8950521.
  2. Al-Waili K, Al-Rasadi K, Al-Bulushi M, Habais M, Al-Mujaini A, Al-Yaarubi S, Rimbert A, Zadjali R, Khaniabadi PM, Al-Barwani H, Hasary S, Al-Dahmani ZM, Al-Badi H, Al-Maawali A, Zadjali F. The Genetic Spectrum of Familial Hypertriglyceridemia in Oman. Front Genet. 2022 May 20;13:886182. doi: 10.3389/fgene.2022.886182. eCollection 2022.PMID: 35669187

 

  1. Alsayed N, Almahmeed W, Alnouri F, Al-Waili K, Sabbour H, Sulaiman K, Zubaid M, Ray KK, Al-Rasadi K. Consensus clinical recommendations for the management of plasma lipid disorders in the Middle East: 2021 update. Atherosclerosis. 2022 Feb;343:28-50. doi: 1016/j.atherosclerosis.2021.11.022. Epub 2021 Dec 10.PMID: 35091265 

 

  1. Al Ismaili AK, Al-Duqhaishi T, Al Rajaibi H, Al Waili K, Al Rasadi K, Nadar SK, Al Hashmi K. Antihypertensive Drugs and Perinatal Outcomes in Hypertensive Women Attending a Specialized Tertiary Hospital. Oman Med J. 2022 Mar 22;37(2):e354. doi: 10.5001/omj.2022.43. eCollection 2022 Mar.PMID: 35356366

 

  1. Chan MF, Ganesh A, Mahadevan S, Shamli SA, Al-Waili K, Al-Mukhaini S, Al-Rasadi K, Al-Adawi S. A Comprehensive Neuropsychological Study of Familial Hypercholesterolemia and Its Relationship with Psychosocial Functioning: A Biopsychosocial Approach. Brain Sci. 2022 Aug 25;12(9):1127. doi: 10.3390/brainsci12091127.PMID: 36138863 

 

  1. Al-Tobi Z, Al Suleimani Y, Al-Rasadi K, Al-Shabibi S, Al Mahrizi A, Al-Maqbali J, Al-Waili K, Al-Adawi S, Al-Zakwani I.
    Metabolic Side Effects of Olanzapine in Patients With Psychotic Disorders in Oman: A Retrospective Cohort Study. Angiology. 2022 Nov-Dec;73(10):976-984. doi: 10.1177/00033197211072340. Epub 2022 Feb 3.PMID: 35113727

 

  1. Al-Sabti H, Al-Hinai AT, Al-Zakwani I, Al-Hashmi K, Al Mahmeed W, Arafah M, Shehab A, Al Tamimi O, Al Awadhi M, Al Herz S, Al Anazi F, Al Nemer K, Metwally O, Alkhadra A, Fakhry M, Elghetany H, Medani AR, Yusufali AH, Al Jassim O, Al Hallaq O, Baslaib FOAS, Amin H, Al-Waili K, Al-Rasadi K. The Achievement of Non-high-density Lipoprotein Cholesterol Target in Patients with Very High Atherosclerotic Cardiovascular Disease Risk Stratified by Triglyceride Levels Despite Statin-controlled Low-density Lipoprotein Cholesterol. Oman Med J. 2022 Mar 22;37(2):e367. doi: 10.5001/omj.2022.79. eCollection 2022 Mar.PMID: 35449790

 

  1. Rizvi AA, Kathuria A, Al Mahmeed W, Al-Rasadi K, Al-Alawi K, Banach M, Banerjee Y, Ceriello A, Cesur M, Cosentino F, Galia M, Goh SY, Janez A, Kalra S, Kempler P, Lessan N, Lotufo P, Papanas N, Santos RD, Stoian AP, Toth PP, Viswanathan V, Rizzo M; CArdiometabolic Panel of International experts on Syndemic COvid-19 (CAPISCO). Post-COVID syndrome, inflammation, and diabetes. J Diabetes Complications. 2022 Nov;36(11):108336. doi: 10.1016/j.jdiacomp.2022.108336. Epub 2022 Oct 6. PMID: 36228563 

 

  1. Gorabi AM, Kiaie N, Khosrojerdi A, Jamialahmadi T, Al-Rasadi K, Johnston TP, Sahebkar A. Implications for the role of lipopolysaccharide in the development of atherosclerosisTrends Cardiovasc Med. 2022 Nov;32(8):525-533. doi: 10.1016/j.tcm.2021.08.015. Epub 2021 Sep 5.PMID: 34492295  

 

  1. Kapoor N, Kalra S, Al Mahmeed W, Al-Rasadi K, Al-Alawi K, Banach M, Banerjee Y, Ceriello A, Cesur M, Cosentino F, Firenze A, Galia M, Goh SY, Janez A, Kempler P, Lessan N, Lotufo P, Papanas N, Rizvi AA, Sahebkar A, Santos RD, Stoian AP, Toth PP, Viswanathan V, Rizzo M; CArdiometabolic Panel of International experts on Syndemic COvid-19 (CAPISCO). The Dual Pandemics of COVID-19 and Obesity: Bidirectional Impact. Diabetes Ther. 2022 Oct;13(10):1723-1736. doi: 10.1007/s13300-022-01311-2. Epub 2022 Aug 27.PMID: 36030317

 

  1. Lo Presti E, Nuzzo D, Al Mahmeed W, Al-Rasadi K, Al-Alawi K, Banach M, Banerjee Y, Ceriello A, Cesur M, Cosentino F, Firenze A, Galia M, Goh SY, Janez A, Kalra S, Kapoor N, Kempler P, Lessan N, Lotufo P, Papanas N, Rizvi AA, Sahebkar A, Santos RD, Stoian AP, Toth PP, Viswanathan V, Rizzo M; CArdiometabolic Panel of International experts on Syndemic COvid-19 (CAPISCO).
    Molecular and pro-inflammatory aspects of COVID-19: The impact on cardiometabolic health. Biochim Biophys Acta Mol Basis Dis. 2022 Dec 1;1868(12):166559. doi: 10.1016/j.bbadis.2022.166559. Epub 2022 Sep 26.PMID: 36174875

 

  1. Jalili-Nik M, Mahboobnia K, Guest PC, Majeed M, Al-Rasadi K, Jamialahmadi T, Sahebkar A. Impact of Curcumin on Hepatic Low-Density Lipoprotein Uptake. Methods Mol Biol. 2022;2343:395-400. doi: 10.1007/978-1-0716-1558-4_29.PMID: 34473340

 

  1. Mainas G, Nibali L, Ide M, Mahmeed WA, Al-Rasadi K, Al-Alawi K, Banach M, Banerjee Y, Ceriello A, Cesur M, Cosentino F, Firenze A, Galia M, Goh SY, Janež A, Kalra S, Kapoor N, Kempler P, Lessan N, Lotufo P, Papanas N, Rizvi AA, Sahebkar A, Santos RD, Stoian AP, Toth PP, Viswanathan V, Rizzo M; CArdiometabolic Panel of International Experts on Syndemic COVID-19 (CAPISCO). Associations between Periodontitis, COVID-19, and Cardiometabolic Complications: Molecular Mechanisms and Clinical Evidence. Metabolites. 2022 Dec 26;13(1):40. doi: 10.3390/metabo13010040.PMID: 36676965

 

  1. Patti AM, Giglio RV, Papanas N, Serban D, Stoian AP, Pafili K, Al Rasadi K, Rajagopalan K, Rizvi AA, Ciaccio M, Rizzo M. Experimental and Emerging Free Fatty Acid Receptor Agonists for the Treatment of Type 2 Diabetes Medicina (Kaunas). 2022 Jan 11;58(1):109. doi: 10.3390/medicina58010109.PMID: 35056417

 

  1. Jamialahmadi T, Reiner Ž, Alidadi M, Almahmeed W, Kesharwani P, Al-Rasadi K, Eid AH, Rizzo M, Sahebkar A. Effect of Bariatric Surgery on Intima Media Thickness: A Systematic Review and Meta-Analysis. J Clin Med. 2022 Oct 13;11(20):6056. doi: 10.3390/jcm11206056.PMID: 36294377 

 

 

  1. Vekic J, Zeljkovic A, Al Rasadi K, Cesur M, Silva-Nunes J, Stoian AP, Rizzo M.Metabolites. A New Look at Novel Cardiovascular Risk Biomarkers: The Role of Atherogenic Lipoproteins and Innovative Antidiabetic Therapies. Metabolites. 2022 Jan 24;12(2):108. doi: 10.3390/metabo12020108.PMID: 35208183 

 

  1. Jamialahmadi T, Guest PC, Tasbandi A, Al-Rasadi K, Sahebkar A. Measuring the Effects of Berberine on Serum Prooxidant-Antioxidant Balance in Metabolic Syndrome. Methods Mol Biol. 2022;2343:309-318. doi: 10.1007/978-1-0716-1558-4_22.PMID: 34473333

 

  1. Zahedipour F, Guest PC, Majeed M, Al-Rasadi K, Jamialahmadi T, Sahebkar A.Multiplex Testing of the Effect of Statins on Disease Severity Risk in COVID-19 Cases.Methods Mol Biol. 2022;2511:273-284. doi: 10.1007/978-1-0716-2395-4_20. PMID: 35838967

 

  1. Jamialahmadi T, Alidadi M, Atkin SL, Kroh M, Almahmeed W, Moallem SA, Al-Rasadi K, Rodriguez JH, Santos RD, Ruscica M, Sahebkar A Effect of Bariatric Surgery on Flow-Mediated Vasodilation as a Measure of Endothelial Function: A Systematic Review and Meta-Analysis.J Clin Med. 2022 Jul 13;11(14):4054. doi: 10.3390/jcm11144054.PMID: 35887817

 

  1. Jensterle M, Herman R, Janež A, Mahmeed WA, Al-Rasadi K, Al-Alawi K, Banach M, Banerjee Y, Ceriello A, Cesur M, Cosentino F, Galia M, Goh SY, Kalra S, Kempler P, Lessan N, Lotufo P, Papanas N, Rizvi AA, Santos RD, Stoian AP, Toth PP, Viswanathan V, Rizzo M. The Relationship between COVID-19 and Hypothalamic-Pituitary-Adrenal Axis: A Large Spectrum from Glucocorticoid Insufficiency to Excess-The CAPISCO International Expert Panel.Int J Mol Sci. 2022 Jun 30;23(13):7326. doi: 10.3390/ijms23137326.PMID: 35806331

 

  1. Alnouri F, Al-Allaf FA, Athar M, Al-Rasadi K, Alammari D, Alanazi M, Abduljaleel Z, Awan Z, Bouazzaoui A, Dairi G, Elbjeirami WM, Karra H, Kinsara AJ, Taher MM.Identification of Novel and Known LDLR Variants Triggering Severe Familial Hypercholesterolemia in Saudi Families. Curr Vasc Pharmacol. 2022;20(4):361-369. doi: 10.2174/1570161120666220304101606.PMID: 35249492

 

Book Chapter:

1.  Chhandak Basu (ed.), PCR Primer Design, Methods in Molecular Biology, vol. 2392, https://doi.org/10.1007/978-1-0716-1799-1_1, © Springer Science+Business Media, LLC, part of Springer Nature 2022.

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