Pathology
  • About Pathology
  • Programs
  • Services
  • Contact Us

Head of Department Message

Welcome to the website of the Department of Pathology, College of Medicine and Health Sciences. The Department is committed to excellence in teaching, research, patient care and community service.  Through teamwork and a collegial and respectful environment, our team of faculty, biomedical scientists and hospital/ college administrative staff are committed to achieving these goals.

Teaching is at the core of the department’s responsibilities. Both faculty and lab scientists are involved in teaching medical students during Phase II, Phase III and Senior Clerkship. The department also offers a practicum for students of the Intercalated program as well as teaching the students of the Biomedical sciences program. The department is also one of the major training sites for Postgraduate Histopathology Residency Program.

The Department offers a subspecialized diagnostic service with faculty members having specific areas of interest. Highly skilled biomedical scientists perform a wide array of specialized laboratory techniques.

The Department is home to the University Wide Electron Microscopy Core Facility supporting undergraduate and postgraduate research in addition to providing diagnostic services both within SQU and beyond.

Faculty members contribute to undergraduate, postgraduate and collaborative research. Several members have grants and a good publication record.

Our commitment to the community is exemplified through regular school visits to our Department as well as our participation in various national exhibition and awareness campaigns to educate the society about diseases and the Pathologist’s role.

As you scroll through the various pages of our website I hope you will find the content both informative and enjoyable.

 

Thank You

Marwa Al Riyami

HOD, Pathology Department

 

 


Department Vision and Mission

 

Vision

To support the vision of SQU and SQUH through the delivery of high-quality Pathology teaching, research and clinical services that is of International Standards as well as community service. 

Mission

The Department of Pathology is committed to providing teaching, research and patient centered care and community service in an environment that supports continuous improvement.

Programs: M.D. Curriculum (Phase II)

 

Course Name

Course Code

Credit hrs

Pathology Contribution

Fall Semester

Response to Infection

MEDI3104

5

8 lectures, 1 tutorials & 6 practicals

Alimentary system

MEDI4303

5

10 lectures, 3 practicals

Uro-reproductive system

MEDI4304

4

6 lectures, 1 tutorial & 3 practicals

Spring Semester

Cardiovascular System

MEDI4204

4

2 lectures, 1 practical

Locomotor System

MEDI4403

3

6 lectures, 4 tutorials

Human Nervous System

MEDI4404

6

3 lectures, 1 tutorial, 1 practical

Endocrine System

MEDI4405

3

5 lectures ,1 tutorial, 1 practical

Respiratory System

MEDI4205

3

5 lectures, 2 practicals

Integrated Module I

MEDI4201

3

 2 tutorials

 

M.D. Curriculum (Phase III)

During their Junior clerkship, students learn about Dermatopathology as part of their Clinical Dermatology rotation.

The senior clerkship students spend two days in the Pathology department as part of the SLT block. They rotate between main histology, cytology, immunohistochemistry and electron microscopy. They also attend the tumor board multidisciplinary meeting.  Over the course of the two days, they learn about how specimens are to be submitted to the lab, both surgical biopsies and cytology samples, all steps involved in lab processing of the specimens and the importance of certain techniques such as frozen section, immunohistochemistry and electron microscopy.

 

 

Biomedical Sciences:

Course Name

Course Code

Credit hrs

Pathology Contribution

Biology of Cancer

MDLS5013

3

8 lectures, 4 tutorials, 3 practicals

Clinical correlations

MDLS5304

3

3 lectures, 1 tutorial

 

Intercalated Programs:

The program runs a histopathology practicum for students of the BSc Health Sciences Program. During this module they learn about laboratory techniques such as microtomy, staining and they dissect small specimens under supervision.

Curriculum Administration

Pathology faculty are active contributors to Curriculum and Assessment through membership of the College Curriculum Committee and Management Committee for Undergraduate Student Research. The Department is also responsible for Coordination of the Alimentary, Locomotor and Integrated I modules (MD program) and Clinical Correlations module (BMS program).

 OMSB Histopathology Residency Program

The department is one of the major training sites for the Oman Medical Specialty Board residency program. The Program Director is a member of the faculty as well as several Trainers and the Chair of the Research subcommittee of the program. Histopathology Residents get to do focused subspecialty reporting. Residents from the Dermatology program, Obs & Gyne program and Hematopathology program also have rotations in the department.

Diagnostic services: 

These include routine diagnostic reports on surgical pathology and cytology specimens. Specialized and comprehensive reporting of tumors of all sizes and types, renal, bone marrow, liver and skin biopsies meet the highest standards of reporting with availability of all specialized techniques. The Department is privileged to have the only Diagnostic Electron microscopy facility in the country which is invaluable in diagnosis of renal and skin diseases and as an adjunct in tumor diagnosis. Participation in urgent reporting on FNAC’s for the one-stop breast clinic and frozen section facility for intra-operative consultation enable real- time decision making for patient management. Second opinions are provided on referred material from other government hospitals and healthcare centers around Oman.

 

Teaching:

Faculty members and biomedical scientists are actively engaged in teaching students of the following degree programmes/courses:

1- M.D Phase I, II, III.

2- B. Sc MLS program

3- Histopathology residents of Oman Medical Specialty Board

4- Training of Omani BMS on request by the Directorate of Training SQUH.

5- Supervision of MD students' research

6- Training in EM techniques

 

Facilities:

The Department provides comprehensive diagnostic facilities through the following sections:

  1. HistoPathology: 

This section includes documentation, grossing, and processing of surgical specimens to generate stained tissue sections for biopsy reporting. A battery of special histochemical stains provides adjunctive information. Frozen section procedures enable critical intraoperative consultation for critical decision-making in-patient management. Macro- and microphotographic facilities provide archiving of interesting cases and enrich presentations and publication efforts.

  1. Cytology: 

The department processes around 4000 cytology specimens annually split between gyne cytology (thin prep) and non-gyne cytology. Experienced cytotechnologists provide rapid on-site assessment (ROSA) in the radiology department for adequacy check of fine needle aspirates.
 

  1. Immunohistochemistry and molecular pathology: 

The department offers a comprehensive range of immunohistochemical stains, immunofluorescence for renal and skin biopsies and enzyme histochemistry techniques for nerve and muscle biopsies. Our biomedical scientists are highly trained with experience in international centers. Molecular pathology includes in situ hybridization as well as immunostains for various molecular markers such as ALK and PD-L1. The department also receives many requests from other hospitals for various markers and for validation.

 

 

  1. Electron microscopy: 

This is regarded as a University wide core facility and is a one of its kind in Oman. It is heavily involved in research but also provides regular diagnostic services to SQUH and other hospitals with a workload of around 350 samples a year. Electron microscopists routinely process and screen renal, cilia, blood, nerve and muscle biopsies for ultrastructural examination.

 

  1. Mortuary: 

The mortuary provides facility for storage of bodies and embalming. No autopsies are performed. 

Department of Pathology

College of Medicine and Health Science

Sultan Qaboos University 

PO Box: 35, Alkoudh.123 Sultanate of Oman

 

College site contact details:

Phone: (+968) 2414-3562, Fax: (+968) 24141198

E-mail:  pathology@squ.edu.om

 

Hospital site contact details:

Phone: (+968) 2414-4974, Fax: (+968) 24144864

E-mail:  pathology.squh@gmail.com

 

Electron Microscopy

  • About Electron Microscopy
  • Facilities
  • Services
  • Facility Use Policies
  • Publications
  • Request Forms
  • Contact information

Welcome to the Electron microscopy core facility (EMCF)

The electron microscopy core facility (EMCF) has started its services in 1989. Only one transmission electron microscope was operating at that time with two EM technologists. Ever since, significant progress has been noticed in terms of staff number, EMs and services provided. From the time it was established, EMCF has contributed substantially providing diagnostic services to government and non-government hospitals side by side with student teaching and research support. Nowadays, EMCF is considered as well-established facility with one field emission TEM, two thermionic TEMs and one SEM. Focusing on diagnostic work, EMCF plays and important role in diagnostic services for the whole of the country. Samples received include renal, muscle, blood and ciliary samples. In terms of research, EMCF get involved in several collaborative research projects with other academic institutions and partner researchers in the country. Moreover, it takes part in teaching SQU students who take courses require EM studies. When highlighting the community service, EMCF is one of the important pillars of the facility that is being always open to school student visits and participating in various local educational activities. 

 

Vision 

The Electron Microscopy Core Facility (EMCF) is a full service and support laboratory that is well equipped to promote research, teaching and training in various disciplines that require biological and material science analysis at ultrastructural level.

Mission 

Delivery of high-quality research, teaching and diagnostic services to better serve the scientific community of SQU and more.

Location 

The facility is located in the Department of Pathology, Ground floor, College of Medicine and Health Sciences.

Electron Microscopes: 

JEOL JEM-2100F: 200 kV FE (Field Emission) analytical electron microscope 

an advanced high resolution field emission  transmission electron microscope equipped with equipped with STEM, ASID, HAADF, EDS, EELS, Holography, Tomography and side mounted CCD Camera (Gatan).

 

JEOL JEM-1200EX:  is a transmission electron microscope with an operating voltage ranging from 40 to 120 kV. It is operating with tungsten filament. It  is mainly used for a life  science research and diagnostic  sample. And it is equipped with, side mounted 4K CCD Camera (AMT).

 

JEOL JEM-1230: is a transmission electron microscope with an operating voltage ranging from 40 to 120 kV. It is operating with tungsten filament. It  is mainly used for a life  science research and diagnostic  sample. It is  equipped with side mount 1K CCD Camera (Gatan)

 

JEOL JSM-5600LV:  Is a Scanning Electron Microscopy that can operate in a  high vacuum and  low vacuum (LV) mode, which is ideal for observing and analysing  non-conductive and wet specimens. It can be operated from 0.5 to 30 KV.  

A wiled range of materials and biological samples  can be examined on this SEM .And it is equipped with Oxford Inca EDS system which can be used in material elemental analysis and mapping.   

 

Sample preparation

 

Medical and Biological Processing Labs

 

                Ultramicrotomes

The ultramicrotome is an instrument commonly used to prepare TEM samples. It uses either a glass or diamond knife to cut ultra thin sections of specimens embedded in epoxy. The sections are approximately 60 to 100 nanometers in thickness and 0.5 to 3 mm in width and can be stained and mounted onto TEM grids for viewing. The ultramicrotome is also used to create mirror-smooth surfaces on samples mounted in epoxy, the applications for which include secondary imaging on the SEM and nanoindentation. Preparation on smooth samples for surface analysis need not always be of samples that are embedded, as sometimes bulk will work.

 

  • Leica Ultracut UCT   
  • Riechert-Jung Ultracut-E
  • Leica ultracut R
  • RMC powerTome XL

 

Tissue Processors

  • Two Leica EM Tissue Processor (EM TP)

 

Cryogenic Equipment

  • Freeze-Substitution System (LEICA EMAFS)
  • Cryopreparation / Cryofixation Station (LEICA EMCPC)
  • JEOL Freeze Drying Device (JFD-310)

 

Accessory Equipment

  • Two Leica EM KMR 2 Knife Makers
  • Leica EM KMR3 Knife Maker
  • Leica EM Stain
  • Pelco Critical Point Drying System (Pelco CPD2)
  • Bio-Rad SEM Coating System
  • Olympus Digital Optical Microscopes
  • Leica Stereo Dissection Microscope
  •  

Materials Preparation Equipment

 

  • Gatan Ion Milling PIPS
  • Gatan TCP
  • Gatan, Disc Grinder
  • Gatan Disc Punch
  • Gatan Dimple Grinder
  • Gatan cooling/healing specimen Holder
  • Automatic Twin-Jet Electropolisher
  • Tenupol Electrolytic thinning

 

Teaching: Electron microscopy staff contribute to the didactic and practical teaching of students of the biomedical sciences program in the College of Medicine and Health Sciences.  In addition, medical students and students from various science colleges in SQU rotate briefly in the EMCF as part of their curricular requirements.

 

Research: The facility provides assistance with research projects for the College of Medicine & Health Sciences, other colleges within SQU as well as governmental and private research centers within the country.

 

Diagnostic: EMCF provides diagnostic services for SQUH, Ministry of Health Hospitals, Armed Forces Hospital and Private sector hospitals/clinics. Diagnostic screening is carried out by the Department Pathologist with the assistance of Senior EM Staff.

 

Training: The facility provides training for SQU Undergraduate and Postgraduate students as well as Technologists from other institutions. Structured training programs are available for both TEM and SEM. The EMCF organizes various workshops periodically focusing on technical as well as interpretive aspects of electron microscopy. .

 

Consultancy: Consultancy services for SQU investigators and scientists from other institution within the country.

 

Community service: The EMCF regularly welcomes high school level students who visit the facility during school days to learn about the electron microscope and the ultrastructure of cells and tissues. These school visits are very popular with positive feedback. In addition, the facility participates in various University and national level exhibitions.

Facility  Use Policies

Electron Microscopy Core Facility (EMCF) at College of Medicine & health Sciences is a multi-user facility and it is imperative that all users work responsibly in the lab.

Access: The Electron Microscopy Core Facility is open Sunday through Thursday from 8:00 am to 4:00 pm. Arrangements can be made for holidays and after working hours to meet investigator’s needs, by contacting the Biomedical Scientist In charge. Most of the major equipment is available for use after hours by prior arrangement.

 

The following rules and regulations must be followed by trainees and staff:

All new users must go through health and safety as well as instrument training from EMCF staff.

EMCF users are not authorized to train fellow group members.

White lab coats and close toed foot wear is mandatory for all lab users.

All hazardous chemicals must be used in the hood and hazardous chemical wastes should be disposed off in their respective waste containers stored under the hood in the waste area.

In case of a spill it is very important that you immediately inform one of the EMCF staff to help you clean up the spill in an efficient and safe way.

Sharps, rubber bulbs, glass rods and other miscellaneous material present in the hood must stay in the hood. They are not to be moved out of the hood under any circumstances. These materials may be contaminated with fixatives.

Any instrument used must be entered into the appropriate logbooks.

Do not insert any hazardous materials/specimens inside EMCF microscopes.

Users are requested to clean up after using any instrumentation in the facility.

If you are the last user of the day, please turn off the microscope high voltage and beam and close the door behind you.

If in doubt about using any equipment or chemical please ask the EMCF staff. Any mistake on your part could put you and others at great risk. Proper chemical handling is expected from all users.

Contact information:

Working hours: Sunday- Thursday 0800 hrs to 1600hrs.

Telephone numbers: 2414-1180, 24143520

Email: emcf@squ.edu.om

Events

2023 Events

Thyroid, Skin Pathology and Laboratory Quality Management Symposium

 

The department organized a two-day Symposium on Thyroid, Skin Pathology and Laboratory Quality Management on 12th and 13th March 2023 at Al Fahm stage, SQU Cultural Center

 

 

Best Practices on Pre-analytical in Pathology workshop
  • The Pathology Department conducted a Workshop of Best Practices on Pre-analytical in Pathology on 28th February 2023, which was presented by an Invited speaker from Rouch Company.

 

School Visits in 2023
  • Musandum governorate school (Female students) visited the EM unit on 12/11/2023.
  • Musandam governorate schools (Male students) visited the EM unit on 15/11/2023.
  • Zaid bin Al Khattab School- Ibri (Male Students) visited the EM unit on 16/11/2023.
  • Jabal Shams School (Female students) visited the EM unit on 28/11/2023.
  • Toam School (international School) visited the EM unit on 30/11/2023.
students fees to free_Event

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Participating in the 3rd Middle East conference on Electron Microscopy- Bahrain on 14th December 2023
  • Dr. Kawther Al Adawi, BMS Senior Specialist, was invited to be a Key note speaker in the 3rd Middle East conference on Electron Microscopy- Bahrain.

Speech Title: “The Missing Beat”

                         

 

  • Mr. Abdurrahman Al Nabhani, Senior Biomedical Sciences, contributed with an oral presentation.

Presentation Title: “The Role of High-Resolution Transmission Electron Microscope in the Applications of Nanotechnology”

 

  • Mr. Mohammed Al Kindi, BMS Senior Specialist, contributed with a poster presentation.

Poster title: “Customized Biochar for Soil Applications in Arid Land: Effect of Feedstock Type and Pyrolysis Temperature on Soil Microbial Enumeration and Respiration”

 

Comference _Event

 

2024 Events

Pathology Department received several School Visits in 2024
  • Abdullah bin Jaafar School – Al Rustaq (Male Students) visited the EM unit on 22/2/2024.
The Pathology Department conducted a TEM Seminar for Life Sciences, which was presented by two invited speakers from Thermofisher Scientific Company on 23rd April 2024
  • Presentation Title: Transmission Electron Microscopy for Life Sciences, Applications and Workflows (Single Particle Analysis, Tomography, Large Volume Analysis) by Mr. Gaurav Sharma, Product Specialist, Cryo-EM, Life Sciences (Netherlands).

Presentation Title: 3D -Visualization” by Mr. Xavier Grandmaison, Sales Manager, EMEA, Visualization and Data Solutions (France).

TEM Seminar for Life Sciences

 

Pathology Department Staff contributed in organizing the International Biomedical Science Day 2024 (????? ????):
  •  Ms. Marwa Al Shukri, Pathology BMS Staff, was a member in the main organizing team of this event.
  • The BMS Pathology Staff: Ahmed Al Shuaibi, Mahmood Al Badowi & Khalfan Al Jabri participated in the exhibition by organizing & moderating the Pathology booth. They focused mainly on: 
  • Showing and explaining how to process the samples in the Pathology labs.
  • The topic of thyroid cancer as one of the most common cancer types that is widely spread in Oman.

 

 

  • Ms. Marwa Al Shukri & Dr. Kawther Al Adawi contributed in organizing and moderating the scientific presentations at this event. 

Pathology Department Staff contributed in organizing the International Biomedical Science Day 2024 (????? ????)

The Principles and use of Light Microscopy workshop
  • Pathology Department conducted a workshop on 5th September 2024 presented by Dr. Kawther Al Adawi, Pathology BMS Senior Specialist. The workshop was held in the Pathology Museum, CoM & HS.

The Principles and use of Light Microscopy workshop